August 21, 2026

Moderna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trialModerna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trialModerna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trial12 NEW DELHI: A personalised cancer vaccine has shown encouraging results in a large Phase-3 trial of patients with high-risk melanoma – a potentially aggressive form of skin cancer – helping keep the cancer from returning or spreading when given along with Merck’s immunotherapy Keytruda, pharma major Moderna said in a statement. Keytruda helps the body’s immune system recognise and attack cancer cells.The INTerpath-001 trial involved 1,137 patients with high-risk melanoma whose tumours had been completely removed through surgery. They received either personalised mRNA treatment, intismeran autogene, along with Keytruda, or Keytruda alone. The combination met the trial’s main goal of improving the time patients remained free of cancer returning and also met a key secondary goal of reducing the risk of the cancer spreading to distant parts of the body.Moderna shares hit a two-year high of $140.19 Wednesday and were on track to add about $30 billion to the company’s market value after promising late-stage data on its personalised mRNA cancer therapy, developed with Merck, sent investors piling into the stock.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelinesAccording to Merck and Moderna, the INTerpath-001 trial met its primary goal of improving recurrence-free survival and a key secondary goal of improving distant metastasis-free survival.Unlike preventive vaccines, this is a therapeutic cancer vaccine designed for people who already have cancer. Dr Mandeep Singh Malhotra, oncologist at Art of Healing Cancer, said the development was an important advance in personalised cancer treatment. But affordability and access would be major challenges in India.Get the latest India News and Live updates. Download the TOI app.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

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Moderna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trialModerna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trialModerna-Merck’s personalised cancer vaccine shows promise in Phase-3 melanoma trial12 NEW DELHI: A personalised cancer vaccine has shown encouraging results in a large Phase-3 trial of patients with high-risk melanoma – a potentially aggressive form of skin cancer – helping keep the cancer from returning or spreading when given along with Merck’s immunotherapy Keytruda, pharma major Moderna said in a statement. Keytruda helps the body’s immune system recognise and attack cancer cells.The INTerpath-001 trial involved 1,137 patients with high-risk melanoma whose tumours had been completely removed through surgery. They received either personalised mRNA treatment, intismeran autogene, along with Keytruda, or Keytruda alone. The combination met the trial’s main goal of improving the time patients remained free of cancer returning and also met a key secondary goal of reducing the risk of the cancer spreading to distant parts of the body.Moderna shares hit a two-year high of 0.19 Wednesday and were on track to add about billion to the company’s market value after promising late-stage data on its personalised mRNA cancer therapy, developed with Merck, sent investors piling into the stock.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelinesAccording to Merck and Moderna, the INTerpath-001 trial met its primary goal of improving recurrence-free survival and a key secondary goal of improving distant metastasis-free survival.Unlike preventive vaccines, this is a therapeutic cancer vaccine designed for people who already have cancer. Dr Mandeep Singh Malhotra, oncologist at Art of Healing Cancer, said the development was an important advance in personalised cancer treatment. But affordability and access would be major challenges in India.Get the latest India News and Live updates. Download the TOI app.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir



NEW DELHI: A personalised cancer vaccine has shown encouraging results in a large Phase-3 trial of patients with high-risk melanoma – a potentially aggressive form of skin cancer – helping keep the cancer from returning or spreading when given along with Merck’s immunotherapy Keytruda, pharma major Moderna said in a statement. Keytruda helps the body’s immune system recognise and attack cancer cells.The INTerpath-001 trial involved 1,137 patients with high-risk melanoma whose tumours had been completely removed through surgery. They received either personalised mRNA treatment, intismeran autogene, along with Keytruda, or Keytruda alone. The combination met the trial’s main goal of improving the time patients remained free of cancer returning and also met a key secondary goal of reducing the risk of the cancer spreading to distant parts of the body.Moderna shares hit a two-year high of $140.19 Wednesday and were on track to add about $30 billion to the company’s market value after promising late-stage data on its personalised mRNA cancer therapy, developed with Merck, sent investors piling into the stock.

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Congress’s post on BJP president Nitin Nabin ‘fabricated’ NEW DELHI: A day after Chhattisgarh Congress posted on social media pictures of BJP president Nitin Nabin having a meal with other party members in Andhra Pradesh and claimed he was consuming meat, BJP accused the party of putting out “fabricated and misleading” content due to its pique over repeated electoral defeats BJP has asserted that it was a vegetarian fare, refuting Congress’ claim that the governing party champions Hindu beliefs but its members were eating meat during the holy month of Sawan.BJP national spokesperson Sudhanshu Trivedi slammed Congress, saying it has resorted to such “cheap antics” because it is mired in the despair of continuous poll defeats. The opposition party had similarly posted fake pictures involving BJP functionaries on Aug 15.”Driven by the frustration and anger over its defeat, it is now using its official social media handles to disseminate false, misleading and entirely fabricated posts,” Trivedi said.The Rajya Sabha MP said Congress’ conduct is not only condemnable politically and ethically but is also an extremely serious matter legally.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

Congress’s post on BJP president Nitin Nabin ‘fabricated’ NEW DELHI: A day after Chhattisgarh Congress posted on social media pictures of BJP president Nitin Nabin having a meal with other party members in Andhra Pradesh and claimed he was consuming meat, BJP accused the party of putting out “fabricated and misleading” content due to its pique over repeated electoral defeats BJP has asserted that it was a vegetarian fare, refuting Congress’ claim that the governing party champions Hindu beliefs but its members were eating meat during the holy month of Sawan.BJP national spokesperson Sudhanshu Trivedi slammed Congress, saying it has resorted to such “cheap antics” because it is mired in the despair of continuous poll defeats. The opposition party had similarly posted fake pictures involving BJP functionaries on Aug 15.”Driven by the frustration and anger over its defeat, it is now using its official social media handles to disseminate false, misleading and entirely fabricated posts,” Trivedi said.The Rajya Sabha MP said Congress’ conduct is not only condemnable politically and ethically but is also an extremely serious matter legally.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

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Encroachment removed outside the Pakistan high commission in Delhi (Credit: Rajesh Mehta) NEW DELHI: Indian authorities removed queue liners outside the Pakistan high commission visa section along with other encroachment on a lane outside the boundary of the compound. The action Wednesday followed removal of parking poles and security barricades outside the Indian high commission in Islamabad earlier this week.Official sources said the liners were removed from a side lane outside the high commission and not the main gate. The response was said to be proportionate to the Pakistani action outside the Indian mission. Official sources said India was hoping the matter would end here but added govt would respond accordingly if Pakistan chooses to escalate.India’s ties with Pakistan remain in a freeze with govt last year — after the Pahalgam terror attack — cutting down the strength of high commissions from the already downgraded 55 to 30. Both sides continue to have functional engagements though, including DGMO-level talks, exchange of pre-notification of flight testing of ballistic missiles, exchange of list of nuclear installations, and exchange of list of prisoners in each other’s custody.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelines India strongly denies having any Track-2 dialogue with Pakistan.Visuals showed that India’s action left a trail of rubble outside the mission, with broken metal railings and gates, twisted metal frames, roofing sheets, bricks and chunks of concrete and plaster strewn across the paved area. The main entrance of the high commission, with its white walls, domed features and large metal gates bearing the Pakistani emblem, remained intact.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

Encroachment removed outside the Pakistan high commission in Delhi (Credit: Rajesh Mehta) NEW DELHI: Indian authorities removed queue liners outside the Pakistan high commission visa section along with other encroachment on a lane outside the boundary of the compound. The action Wednesday followed removal of parking poles and security barricades outside the Indian high commission in Islamabad earlier this week.Official sources said the liners were removed from a side lane outside the high commission and not the main gate. The response was said to be proportionate to the Pakistani action outside the Indian mission. Official sources said India was hoping the matter would end here but added govt would respond accordingly if Pakistan chooses to escalate.India’s ties with Pakistan remain in a freeze with govt last year — after the Pahalgam terror attack — cutting down the strength of high commissions from the already downgraded 55 to 30. Both sides continue to have functional engagements though, including DGMO-level talks, exchange of pre-notification of flight testing of ballistic missiles, exchange of list of nuclear installations, and exchange of list of prisoners in each other’s custody.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelines India strongly denies having any Track-2 dialogue with Pakistan.Visuals showed that India’s action left a trail of rubble outside the mission, with broken metal railings and gates, twisted metal frames, roofing sheets, bricks and chunks of concrete and plaster strewn across the paved area. The main entrance of the high commission, with its white walls, domed features and large metal gates bearing the Pakistani emblem, remained intact.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

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One of CARA’s key focus areas is stepping up adoption of children with special needs NEW DELHI: Central Adoption Resource Authority announced Thursday that it was undertaking a review of the adoption regulations notified in 2022 in order to strengthen the regulatory framework and address “emerging legal, procedural and implementation-related issues”.The 2022 regulations had marked a significant shift, wi-th district magistrates getting the power to issue adoption orders in place of district courts.In the public notice issued Thursday, CARA invited comments and suggestions from the public and organisations on the provisions of the 2022 regulations that may require amendment, insertion, substitution or omission. The last day for submitting suggestions is Sept 9.Thereafter, CARA proposes to hold consultations with stakeholders to firm up the review before drafting a proposal for amendments. This, too, will be put in the public domain before being finalised, sources said.According to officials, it was felt that despite the significant changes in 2022, there were some areas that were still ambiguous. “For now, such issues are dealt with through office orders and letters to interpret certain clauses in keeping with the law. The review will address such concerns in consultation with key stakeholders to bring clarity,” an official said.It is learned that one of the key focus areas CARA is working on is stepping up adoption of special needs children. One of the things being explored is whether a sub-category can be created for children with temporary or treatable conditions, like a cleft lip, to enhance the potential for adoption in such cases, sources said.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelinesAccording to the CARA website, out of 5,022 children adopted between April 2025 and March 2026, just 392 were in the special needs category. Of them, only 84 children figured in the domestic adoption category with the remaining 308 adoptions taking place in the inter-country adoptions category.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

One of CARA’s key focus areas is stepping up adoption of children with special needs NEW DELHI: Central Adoption Resource Authority announced Thursday that it was undertaking a review of the adoption regulations notified in 2022 in order to strengthen the regulatory framework and address “emerging legal, procedural and implementation-related issues”.The 2022 regulations had marked a significant shift, wi-th district magistrates getting the power to issue adoption orders in place of district courts.In the public notice issued Thursday, CARA invited comments and suggestions from the public and organisations on the provisions of the 2022 regulations that may require amendment, insertion, substitution or omission. The last day for submitting suggestions is Sept 9.Thereafter, CARA proposes to hold consultations with stakeholders to firm up the review before drafting a proposal for amendments. This, too, will be put in the public domain before being finalised, sources said.According to officials, it was felt that despite the significant changes in 2022, there were some areas that were still ambiguous. “For now, such issues are dealt with through office orders and letters to interpret certain clauses in keeping with the law. The review will address such concerns in consultation with key stakeholders to bring clarity,” an official said.It is learned that one of the key focus areas CARA is working on is stepping up adoption of special needs children. One of the things being explored is whether a sub-category can be created for children with temporary or treatable conditions, like a cleft lip, to enhance the potential for adoption in such cases, sources said.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelinesAccording to the CARA website, out of 5,022 children adopted between April 2025 and March 2026, just 392 were in the special needs category. Of them, only 84 children figured in the domestic adoption category with the remaining 308 adoptions taking place in the inter-country adoptions category.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

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Bribe demand unproven, Rs 20 note no proof: SC acquits 2 NEW DELHI: Thirty years after they were accused of taking a bribe of Rs 20 to issue an income certificate, Supreme Court has acquitted two govt employees in a 1996 corruption case in which they were convicted and sentenced to one year’s imprisonment by a trial court.A bench of Justices Ujjal Bhuyan and Atul S Chandurkar held that the govt employees were wrongly convicted in the case as there was no evidence that they had demanded the bribe. The aggrieved employees, now senior citizens, had to fight legal battles for three decades to prove their innocence. They were sacked from govt jobs after conviction.”We find on an appreciation of the entire material brought on record by the prosecution that it falls woefully short of proving the charge against both the accused beyond reasonable doubt,” the bench said. The court noted that the demand of bribe was an essential ingredient to convict a person in a corruption case and that was missing in the case.”When any demand was not proved, as held by both the Courts, it was clear that the complainant had thrust the note of ₹20/- in the pocket of accused number 2 without any demand. The defence as raised that the festival of Eid was to be celebrated on the next day and it was for that purpose that the complainant had given the note of Rs 20/- after receiving the necessary certificate, therefore, assumed significance,” the bench said.As per the prosecution case, the clerk had demanded Rs 120 (Rs 100 for himself and Rs 20 for the peon) for issuing an income certificate. The complainant subsequently approached the Anti-Corruption Bureau (ACB), which organised a trap. The complainant along with the raiding party visited the office and according to prosecution, on receiving such certificate the complainant gave a note of Rs 20/- to A2 who put it in his pocket.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelines On giving pre-determined signal, the raiding party appeared and, thereafter, drew the necessary panchnama.Allowing relief to the accused, the bench said, “…mere possession of a currency note of Rs 20/- with A2 by itself would not be sufficient to uphold the conviction of A1 and A2 for the offence,” the court said.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

Bribe demand unproven, Rs 20 note no proof: SC acquits 2 NEW DELHI: Thirty years after they were accused of taking a bribe of Rs 20 to issue an income certificate, Supreme Court has acquitted two govt employees in a 1996 corruption case in which they were convicted and sentenced to one year’s imprisonment by a trial court.A bench of Justices Ujjal Bhuyan and Atul S Chandurkar held that the govt employees were wrongly convicted in the case as there was no evidence that they had demanded the bribe. The aggrieved employees, now senior citizens, had to fight legal battles for three decades to prove their innocence. They were sacked from govt jobs after conviction.”We find on an appreciation of the entire material brought on record by the prosecution that it falls woefully short of proving the charge against both the accused beyond reasonable doubt,” the bench said. The court noted that the demand of bribe was an essential ingredient to convict a person in a corruption case and that was missing in the case.”When any demand was not proved, as held by both the Courts, it was clear that the complainant had thrust the note of ₹20/- in the pocket of accused number 2 without any demand. The defence as raised that the festival of Eid was to be celebrated on the next day and it was for that purpose that the complainant had given the note of Rs 20/- after receiving the necessary certificate, therefore, assumed significance,” the bench said.As per the prosecution case, the clerk had demanded Rs 120 (Rs 100 for himself and Rs 20 for the peon) for issuing an income certificate. The complainant subsequently approached the Anti-Corruption Bureau (ACB), which organised a trap. The complainant along with the raiding party visited the office and according to prosecution, on receiving such certificate the complainant gave a note of Rs 20/- to A2 who put it in his pocket.Join conversationView All Comments →Share your thoughts in the commentsInsightfulAgreeDisagreeSkepticalConcerningPromisingWorth ReadingBig DevelopmentPost CommentBe respectful · TOI community guidelines On giving pre-determined signal, the raiding party appeared and, thereafter, drew the necessary panchnama.Allowing relief to the accused, the bench said, “…mere possession of a currency note of Rs 20/- with A2 by itself would not be sufficient to uphold the conviction of A1 and A2 for the offence,” the court said.Get the latest India News and Live updates. Download the TOI app.End of ArticleFollow Us On Social MediaVideos‘NEET, Delimitation, Cauvery, Drugs’: Vijay’s Key Requests Before Amit Shah At Tamil Nadu MeetingPolicy Shift Or Just Words? Inside US Envoy Gor’s ‘Kashmir’ Remark That Rattled PakistanJharkhand High Court Stays Soren Govt’s Order To Cancel JPSC Exams, AppointmentsKangana Vs Ramdev: BJP MP Fires Back After Yoga Guru Questions Her Past And Controversial Remarks’Not Mahatma Gandhi’s Congress’: FULL Vande Mataram Rejected At INC Events, BJP Doubts ‘Loyalty’US Body Opposes Mohan Bhagwat’s Visit, Seeks Sanctions on RSS Members Over Religious Freedom ClaimsDJB Tender Scam Row: AAP Questions Why Raghav Chadha Was Never Questioned By InvestigatorsMaharashtra’s Power Shift: Fadnavis Can Now Reverse Ministerial Decisions In Public InterestIndia Removes Pakistan Mission Barricades After Islamabad Move, Tensions Rise Over Kashmir RemarksModi Govt’s Gen-Z Outreach: One Union Minister To Visit One University Daily123PhotostoriesHow to look expensive without spending a lot of moneyFrom money plants to shankh: 5 Vastu items believed to bring good luck and positivity at homeHow much walking can reverse the health risks of sitting for 8 hours a day? Doctor explains what your body needsWhy does homemade curd turn slimy during monsoon and 3 ways to prevent itThe history of the white shirt: How a simple staple became the ultimate fashion icon10 enchanting baby girl names inspired by fantasy, mythology and folkloreSugar price hike by Rs 8 per kg: 9 natural Indian sweeteners and how to use themOptical illusion personality test: The first thing you spot reveals what’s coming next in your lifeIs apple cider vinegar good for your hair? Benefits, side effects, and the right way to use it10 One Piece characters who have lived for more than a 100 years123Hot PicksPeru EarthquakeConnor McDavidGTU results 2026Pennsylvania plane crashOil export IndiaFaceless assessmentRSS sanctionZepto internshipPakistan High CommissionTop TrendingHyderabad MurderPakistan High CommissionTwisha SharmaKarnataka MurderKerala MurderAbhijeet DipkeSukesh ChandrashekharRahul GandhiBengaluru RapidoBen Gvir

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