May 19, 2026
‘Batter has every right’: Ashwin supports Daryl Mitchell after Usman Tariq’s ‘Pause’ drama in PSL

‘Batter has every right’: Ashwin supports Daryl Mitchell after Usman Tariq’s ‘Pause’ drama in PSL

Vamsikrishna02 mins mins

PSL drama over Usman Tariq pause (Screengrab) Former India all-rounder Ravichandran Ashwin has come out in support of Daryl Mitchell after the New Zealand batter raised concerns over Usman Tariq’s unusual delivery pause during a Pakistan Super League (PSL) 2026 clash in Karachi.The incident occurred during the match between Quetta Gladiators and Rawalpindi, where Mitchell…

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US-Iran conflict: At nearly 0 billion, how India’s forex reserves are a strong armour against global crises

US-Iran conflict: At nearly $700 billion, how India’s forex reserves are a strong armour against global crises

Vamsikrishna013 mins mins

India’s forex reserves have become more balanced over time, with more gold and some diversification beyond the US dollar. (AI image) A country’s foreign exchange reserves act as the first line of defence against external volatility. In times of global economic turmoil such as the present Middle East conflict, forex reserves are the armour that…

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Jessica Biel addresses the viral ‘Jessica Tantrum’ trend: Says ‘On behalf of all Jessicas, we are nice people’

Jessica Biel addresses the viral ‘Jessica Tantrum’ trend: Says ‘On behalf of all Jessicas, we are nice people’

Vamsikrishna03 mins mins

Actress Jessica Biel has taken to social media to confront a troubling new trend known as the ‘Jessica Tantrum.’ It seems some parents are yelling ‘Jessica’ at their tantruming toddlers to calm them down. In her heartfelt message, Biel expressed her worry about the fear this instills in young children, suggesting that they appear ‘petrified….

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Representational image NEW DELHI: Residents of Ladakh will now have “Ladakh” instead of “Jammu & Kashmir” in their Aadhaar cards, in what has been described as a “significant move” to uphold their regional identity. Despite the formation of Ladakh as a Union territory in 2019, after the region was carved out of Jammu and Kashmir, which was also made a Union territory, the Aadhaar records of its residents had continued to reflect the erstwhile state’s name. According to a press release, lieutenant governor Vinai Kumar Saxena took serious note of the issue and directed the Ladakh administration to resolve it at the earliest. The administration subsequently took up the matter with the Unique Identification Authority of India (UIDAI), the central body responsible for issuing Aadhaar cards. “The continued reflection of ‘Jammu and Kashmir’ in Aadhaar records of Ladakh residents had been causing considerable inconvenience. Residents faced difficulties in using the document as valid identity and address proof while availing various services, as the ‘state’ field did not correspond to Ladakh’s post-reorganisation status,” the release said. The issue also affected the proper representation of Ladakh in Aadhaar-linked records and progress reports. To address this, the administration and UIDAI devised an innovative mechanism to update the “state” field centrally. Instead of requiring residents to individually visit Aadhaar centres, the updation was carried out using PIN codes specific to Ladakh. These were verified in coordination with the India Post and shared with UIDAI.About the AuthorTOI News DeskThe TOI News Desk comprises a dedicated and tireless team of journalists who operate around the clock to deliver the most current and comprehensive news and updates to the readers of The Times of India worldwide. With an unwavering commitment to excellence in journalism, our team is at the forefront of gathering, verifying, and presenting breaking news, in-depth analysis, and insightful reports on a wide range of topics. The TOI News Desk is your trusted source for staying informed and connected to the ever-evolving global landscape, ensuring that our readers are equipped with the latest developments that matter most.”Read MoreEnd of ArticleFollow Us On Social MediaVideosNitish Kumar’s Rajya Sabha Oath Triggers Bihar Leadership Buzz: Who Will Be the Next CM?Mirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha Visit123PhotostoriesWhy you should avoid certain types of sprouts and 3 common mistakes to avoid while consuming themDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

Representational image NEW DELHI: Residents of Ladakh will now have “Ladakh” instead of “Jammu & Kashmir” in their Aadhaar cards, in what has been described as a “significant move” to uphold their regional identity. Despite the formation of Ladakh as a Union territory in 2019, after the region was carved out of Jammu and Kashmir, which was also made a Union territory, the Aadhaar records of its residents had continued to reflect the erstwhile state’s name. According to a press release, lieutenant governor Vinai Kumar Saxena took serious note of the issue and directed the Ladakh administration to resolve it at the earliest. The administration subsequently took up the matter with the Unique Identification Authority of India (UIDAI), the central body responsible for issuing Aadhaar cards. “The continued reflection of ‘Jammu and Kashmir’ in Aadhaar records of Ladakh residents had been causing considerable inconvenience. Residents faced difficulties in using the document as valid identity and address proof while availing various services, as the ‘state’ field did not correspond to Ladakh’s post-reorganisation status,” the release said. The issue also affected the proper representation of Ladakh in Aadhaar-linked records and progress reports. To address this, the administration and UIDAI devised an innovative mechanism to update the “state” field centrally. Instead of requiring residents to individually visit Aadhaar centres, the updation was carried out using PIN codes specific to Ladakh. These were verified in coordination with the India Post and shared with UIDAI.About the AuthorTOI News DeskThe TOI News Desk comprises a dedicated and tireless team of journalists who operate around the clock to deliver the most current and comprehensive news and updates to the readers of The Times of India worldwide. With an unwavering commitment to excellence in journalism, our team is at the forefront of gathering, verifying, and presenting breaking news, in-depth analysis, and insightful reports on a wide range of topics. The TOI News Desk is your trusted source for staying informed and connected to the ever-evolving global landscape, ensuring that our readers are equipped with the latest developments that matter most.”Read MoreEnd of ArticleFollow Us On Social MediaVideosNitish Kumar’s Rajya Sabha Oath Triggers Bihar Leadership Buzz: Who Will Be the Next CM?Mirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha Visit123PhotostoriesWhy you should avoid certain types of sprouts and 3 common mistakes to avoid while consuming themDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

Vamsikrishna02 mins mins

NEW DELHI: Residents of Ladakh will now have “Ladakh” instead of “Jammu & Kashmir” in their Aadhaar cards, in what has been described as a “significant move” to uphold their regional identity. Despite the formation of Ladakh as a Union territory in 2019, after the region was carved out of Jammu and Kashmir, which was…

Read More
From queues to QR codes: How UPI transformed India’s digital payments, now driving 49% of global real-time transactions

From queues to QR codes: How UPI transformed India’s digital payments, now driving 49% of global real-time transactions

Vamsikrishna04 mins mins

India’s financial ecosystem has undergone a major transformation in recent years, with the Unified Payments Interface (UPI) emerging as the centrepiece of the country’s digital payments revolution. Just ten years ago, financial transactions in the country were slow and largely cash-dependent but now, they are just a touch or click away, enabling instant, seamless and…

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Jason Segel spills beans on security being called on him in Finland over ‘friendly’ American habit: Here’s what happened

Jason Segel spills beans on security being called on him in Finland over ‘friendly’ American habit: Here’s what happened

Vamsikrishna02 mins mins

Imagine spending time in a foreign country, trying to be friendly with strangers, and ending up being called out on it!Jason Segel learned pretty quickly that being an ‘overfriendly’ American can get you in trouble in Finland, and not in the way you’d expect. On a recent visit, he actually got security called on him…

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Who is Amit Kshatriya? Indian-American Nasa official behind historic Moon mission

Who is Amit Kshatriya? Indian-American Nasa official behind historic Moon mission

Vamsikrishna02 mins mins

Indian-American space scientist Amit Kshatriya holds a senior leadership position at Nasa, an agency that has recently completed the Artemis II mission, a significant step in its renewed human lunar exploration programme.The Artemis II mission, a crewed lunar flyby, concluded with astronauts returning safely after a splashdown off the coast of San Diego, California at…

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Uae News: Air Arabia resumes flights to 49 destinations from UAE: Services restart from Sharjah, Abu Dhabi and Ras Al Khaimah | World News

Uae News: Air Arabia resumes flights to 49 destinations from UAE: Services restart from Sharjah, Abu Dhabi and Ras Al Khaimah | World News

Vamsikrishna02 mins mins

Amid the ongoing regional tensions in the Middle East, airlines have started resuming flight services to international destinations gradually. With appropriate permissions from authorities and mindfully created schedules, the region’s connectivity to the globe is back on track.Now, Air Arabia has announced that it will operate flights from Sharjah, Abu Dhabi and Ras Al Khaimah…

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. Meet Mr Bipin. He is nearing 62. These days, he pauses before signing his name, his hand trembling as he tries to steady the pen. What was once a simple task now takes great effort. His movements have slowed, his steps have become shorter, and at times he shuffles or loses balance without warning.Mr Bipin, who once never missed his evening walk around the house, now skips it almost every day. His body often feels stiff, his face less expressive than before. At night, his sleep is restless, and during the day, an unshakeable fatigue and anxiety leave him constantly unsettled and drained.At first, the signs are easy to dismiss as aging, stress, or just “weakness,” as some say. The sudden tremor draws curious glances, the slowness draws impatience, even from his family members at times. Conversations begin to feel effortful, and gradually, he starts withdrawing, reluctant to explain what he himself doesn’t fully understand.For months, the symptoms remain unnamed, often dismissed as stress or ageing, until a clinical diagnosis brings difficult clarity: he has Parkinson’s disease, one of the fastest-growing neurological conditions globally, affecting nearly 10 million people worldwide.What is Parkinson’s disease?According to WHO, Parkinson’s disease (PD) is a progressive neurodegenerative brain disorder that causes problems with movement, mental health, sleep, pain and other health issues.It develops when nerve cells in a part of the brain called the substantia nigra gradually become damaged or die. These cells normally produce dopamine, a chemical that helps coordinate smooth and controlled muscle movement. As dopamine levels decrease, the brain’s ability to regulate movement becomes impaired.The condition most commonly affects motor skills, coordination, and causes tremors (involuntary shaking), slowness of movement (bradykinesia), muscle stiffness, and problems with balance and coordination. Over time, people may also experience changes in posture, reduced facial expression, softer speech, and smaller handwriting. Beyond movement-related symptoms, Parkinson’s can also affect sleep, cognition, hearing ability, mood, memory, and overall energy levels.Parkinson’s disease is long-term and progressive, meaning symptoms typically worsen gradually over time, though the rate of progression varies widely from person to person.What causes Parkinson’s disease?The exact cause of Parkinson’s disease is still not fully understood. It is now widely accepted that the condition develops due to a combination of biological changes in the brain, along with genetic and environmental risk factors over time.At the core of the disease is the gradual loss of dopamine-producing neurons in a region of the brain called the substantia nigra. This leads to reduced dopamine levels, which disrupt the brain circuits responsible for smooth and coordinated movement.Another key feature seen in Parkinson’s is the abnormal accumulation of a protein called alpha-synuclein. This protein forms clumps known as Lewy bodies inside nerve cells and is strongly linked to nerve cell dysfunction and degeneration.Researchers believe several factors may contribute to these changes, including age, genetic susceptibility in a small proportion of cases, and environmental exposures such as pesticides and certain toxins. However, no single cause has been identified, and in most patients, the disease appears to develop sporadically without a clear trigger.Beyond tremors: The hidden side of Parkinson’sParkinson’s is often associated with visible symptoms: tremors, stiffness, and slowed movement. But medically, it is a progressive neurological condition that begins deep within the brain. It develops when nerve cells that produce dopamine, a chemical essential for smooth, coordinated movement, gradually deteriorate. As dopamine levels fall, the brain’s ability to control movement and coordination weakens. Parkinson’s diseaseWhile motor symptoms are the most recognisable, the disease extends far beyond movement. Non-motor symptoms, often subtle and easy to miss, can appear years before tremors or stiffness. These include sleep disturbances, fatigue, mood changes, loss of smell, and cognitive slowing, making Parkinson’s as much a behavioural and psychological condition as a physical one.Non-motor symptoms: the missed early warning signsSpeaking to TOI, Dr Riaz Ahamed Syed, paediatric neurologist with over four decades of experience, explained that Parkinson’s is often misunderstood as a movement disorder alone, while a large part of its burden comes from symptoms that are less visible.“Most people think of tremors, rigidity, and slowness. But a large part of the disease lies in non-motor symptoms, which are frequently missed,” he said.According to him, mood-related changes such as anxiety, depression, and apathy, along with slowing of thought and cognitive decline, are common but under-recognised. Patients may also experience loss of smell, constipation, urinary urgency, sleep disturbances, and difficulty swallowing, symptoms that can appear years before the classic motor signs. .“These symptoms are non-specific and often ignored. But if recognised early, we can begin treatment sooner and manage the condition better,” he added.Treatment and managing symptomsParkinson’s is a progressive and degenerative condition, meaning symptoms tend to worsen over time. At present, there is no definitive cure, but treatment can significantly improve quality of life.“In younger patients, we may start with dopamine agonists, which help increase dopamine activity in the brain. After the age of 50, medications like levodopa are more commonly used,” Dr Syed explained.Other drugs, including MAO inhibitors and amantadine, may also be prescribed depending on the patient’s condition. In more advanced cases, therapies like deep brain stimulation can help control severe tremors.“The focus should be on consistent medication, regular follow-ups, and proper management, rather than looking for a permanent cure,” he said.Who is at risk?Age remains the strongest risk factor, with most cases developing after the age of 60. However, Parkinson’s is not exclusively a disease of the elderly; early-onset cases can occur, sometimes even before 50.The exact cause remains unclear, but experts believe a mix of genetic predisposition and environmental exposure plays a role. Individuals with a family history of Parkinson’s may have a higher risk, as may those exposed to certain toxins or pesticides over time.Men are slightly more likely to develop the condition than women, though the reasons are still being studied.Despite these risk factors, many patients, like Mr Bipin, develop Parkinson’s without any clear warning or identifiable cause.The invisible burden: Caregiving and social stigmaBeyond the physical symptoms lies a deeper, often unspoken challenge: social and emotional isolation.Patients may gradually withdraw from social interactions, not because they want to, but because the disease makes communication and movement difficult. Slowed speech, reduced facial expressions, and physical limitations can be misinterpreted as disinterest or disengagement.“Patients tend to withdraw, and families sometimes don’t understand why,” Dr Syed said.Where awareness remains limited, this can lead to stigma, misunderstanding, and delayed care. At the same time, it can add to the emotional and physical toll on families taking on the role of caregivers, managing medications, daily routines, and emotional needs.Everyday challengesParkinson’s affects even the simplest daily activities. Tasks like getting up from a chair, turning while walking, going to the washroom, or swallowing food can become difficult.“One misconception is that patients should try to move faster. This can actually increase the risk of falls,” Dr Syed cautioned.He emphasised the need to adapt the environment, from using assistive devices to modifying diets. Soft or semi-solid foods can help those with swallowing difficulties, while fibre-rich diets can ease constipation, a common issue.Physiotherapy and rehabilitation, he added, are essential in maintaining mobility and independence.The “million-dollar question”: Can Parkinson’s disease be cured?Dr Syed addressed one of the most frequently asked concerns, which he referred to as the “million-dollar question” asked by patients and families about whether Parkinson’s disease has a permanent cure. He explained that it is a progressive, degenerative disorder that worsens over time and currently has no definitive cure, though treatment can help manage symptoms and improve quality of life.“The million-dollar question being asked is, Doc, can I have a permanent cure? We all know Parkinson’s disease is a progressive disorder, a degenerative disorder, and as years go by, patients tend to deteriorate. There are staging processes of Parkinson’s being done. But the million-dollar question is: can I have a permanent cure? Unfortunately, at this point in time, there is no specific cure for Parkinson’s disease.”While there is currently no cure, a combination of medications, physical therapy, lifestyle adjustments, and, in some cases, surgical treatments can help manage symptoms and improve quality of life.Why this conversation matters nowOn World Parkinson’s Day, the focus is not just on the disease itself, but on awareness, early detection, and support systems.According to a study titled Neuropalliative Care for Parkinson’s Disease in India, the prevalence of Parkinson’s disease (PD) in India accounts for roughly 10% of the global burden, making it a significant public health concern.Experts at the 6th International Annual Symposium-2026 in Kerala said that India is expected to witness a surge in Parkinson’s cases in the coming years, which may pose a growing burden on families and caregivers. Yet awareness of early symptoms and non-motor signs remains low.The need is not only for better treatment, but for earlier recognition, reduced stigma, and stronger support networks, so that patients are not left navigating the condition in silence.Looking aheadWhile there is no cure yet, ongoing research offers cautious optimism. New drug delivery systems and emerging therapies, including stem cell research particularly induced pluripotent stem cells and human pluripotent stem cells, are being explored.For now, doctors emphasise a holistic approach, combining medication, mental health support, physiotherapy, and family involvement.“Parkinson’s is not just about tremors or movement. It affects the entire life of the patient and the family,” Dr Syed said.Parkinson’s disease is increasingly being recognised as a condition that begins long before visible symptoms such as tremors appear. Evidence suggests that more than half of dopamine-producing neurons in the brain may already be lost by the time a clinical diagnosis is made, underlining how silently the disease progresses in its early stages.This makes early recognition of non-motor symptoms such as sleep disturbances, loss of smell, mood changes, and constipation especially important. Greater awareness among families and caregivers can help ensure earlier medical attention, timely diagnosis, and better symptom management.At the same time, experts emphasise that medical care alone is not enough. Social acceptance and understanding play a critical role, as patients often face isolation due to slowed speech, reduced facial expression, and movement difficulties that are frequently misunderstood. Reducing stigma can go a long way in improving mental well-being and quality of life.About the AuthorOshin BhatiaOshin Bhatia is a budding journalist driven by an insatiable curiosity and hunger for knowledge. She loves diving deep into complex issues and expressing them through compelling narratives. Her interests span human-interest stories, the environment, and the intersections where people, places, and stories meet.Read MoreEnd of ArticleFollow Us On Social MediaVideosMirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North India123PhotostoriesDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit4 high-profile business family feuds that made headlines globally123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

. Meet Mr Bipin. He is nearing 62. These days, he pauses before signing his name, his hand trembling as he tries to steady the pen. What was once a simple task now takes great effort. His movements have slowed, his steps have become shorter, and at times he shuffles or loses balance without warning.Mr Bipin, who once never missed his evening walk around the house, now skips it almost every day. His body often feels stiff, his face less expressive than before. At night, his sleep is restless, and during the day, an unshakeable fatigue and anxiety leave him constantly unsettled and drained.At first, the signs are easy to dismiss as aging, stress, or just “weakness,” as some say. The sudden tremor draws curious glances, the slowness draws impatience, even from his family members at times. Conversations begin to feel effortful, and gradually, he starts withdrawing, reluctant to explain what he himself doesn’t fully understand.For months, the symptoms remain unnamed, often dismissed as stress or ageing, until a clinical diagnosis brings difficult clarity: he has Parkinson’s disease, one of the fastest-growing neurological conditions globally, affecting nearly 10 million people worldwide.What is Parkinson’s disease?According to WHO, Parkinson’s disease (PD) is a progressive neurodegenerative brain disorder that causes problems with movement, mental health, sleep, pain and other health issues.It develops when nerve cells in a part of the brain called the substantia nigra gradually become damaged or die. These cells normally produce dopamine, a chemical that helps coordinate smooth and controlled muscle movement. As dopamine levels decrease, the brain’s ability to regulate movement becomes impaired.The condition most commonly affects motor skills, coordination, and causes tremors (involuntary shaking), slowness of movement (bradykinesia), muscle stiffness, and problems with balance and coordination. Over time, people may also experience changes in posture, reduced facial expression, softer speech, and smaller handwriting. Beyond movement-related symptoms, Parkinson’s can also affect sleep, cognition, hearing ability, mood, memory, and overall energy levels.Parkinson’s disease is long-term and progressive, meaning symptoms typically worsen gradually over time, though the rate of progression varies widely from person to person.What causes Parkinson’s disease?The exact cause of Parkinson’s disease is still not fully understood. It is now widely accepted that the condition develops due to a combination of biological changes in the brain, along with genetic and environmental risk factors over time.At the core of the disease is the gradual loss of dopamine-producing neurons in a region of the brain called the substantia nigra. This leads to reduced dopamine levels, which disrupt the brain circuits responsible for smooth and coordinated movement.Another key feature seen in Parkinson’s is the abnormal accumulation of a protein called alpha-synuclein. This protein forms clumps known as Lewy bodies inside nerve cells and is strongly linked to nerve cell dysfunction and degeneration.Researchers believe several factors may contribute to these changes, including age, genetic susceptibility in a small proportion of cases, and environmental exposures such as pesticides and certain toxins. However, no single cause has been identified, and in most patients, the disease appears to develop sporadically without a clear trigger.Beyond tremors: The hidden side of Parkinson’sParkinson’s is often associated with visible symptoms: tremors, stiffness, and slowed movement. But medically, it is a progressive neurological condition that begins deep within the brain. It develops when nerve cells that produce dopamine, a chemical essential for smooth, coordinated movement, gradually deteriorate. As dopamine levels fall, the brain’s ability to control movement and coordination weakens. Parkinson’s diseaseWhile motor symptoms are the most recognisable, the disease extends far beyond movement. Non-motor symptoms, often subtle and easy to miss, can appear years before tremors or stiffness. These include sleep disturbances, fatigue, mood changes, loss of smell, and cognitive slowing, making Parkinson’s as much a behavioural and psychological condition as a physical one.Non-motor symptoms: the missed early warning signsSpeaking to TOI, Dr Riaz Ahamed Syed, paediatric neurologist with over four decades of experience, explained that Parkinson’s is often misunderstood as a movement disorder alone, while a large part of its burden comes from symptoms that are less visible.“Most people think of tremors, rigidity, and slowness. But a large part of the disease lies in non-motor symptoms, which are frequently missed,” he said.According to him, mood-related changes such as anxiety, depression, and apathy, along with slowing of thought and cognitive decline, are common but under-recognised. Patients may also experience loss of smell, constipation, urinary urgency, sleep disturbances, and difficulty swallowing, symptoms that can appear years before the classic motor signs. .“These symptoms are non-specific and often ignored. But if recognised early, we can begin treatment sooner and manage the condition better,” he added.Treatment and managing symptomsParkinson’s is a progressive and degenerative condition, meaning symptoms tend to worsen over time. At present, there is no definitive cure, but treatment can significantly improve quality of life.“In younger patients, we may start with dopamine agonists, which help increase dopamine activity in the brain. After the age of 50, medications like levodopa are more commonly used,” Dr Syed explained.Other drugs, including MAO inhibitors and amantadine, may also be prescribed depending on the patient’s condition. In more advanced cases, therapies like deep brain stimulation can help control severe tremors.“The focus should be on consistent medication, regular follow-ups, and proper management, rather than looking for a permanent cure,” he said.Who is at risk?Age remains the strongest risk factor, with most cases developing after the age of 60. However, Parkinson’s is not exclusively a disease of the elderly; early-onset cases can occur, sometimes even before 50.The exact cause remains unclear, but experts believe a mix of genetic predisposition and environmental exposure plays a role. Individuals with a family history of Parkinson’s may have a higher risk, as may those exposed to certain toxins or pesticides over time.Men are slightly more likely to develop the condition than women, though the reasons are still being studied.Despite these risk factors, many patients, like Mr Bipin, develop Parkinson’s without any clear warning or identifiable cause.The invisible burden: Caregiving and social stigmaBeyond the physical symptoms lies a deeper, often unspoken challenge: social and emotional isolation.Patients may gradually withdraw from social interactions, not because they want to, but because the disease makes communication and movement difficult. Slowed speech, reduced facial expressions, and physical limitations can be misinterpreted as disinterest or disengagement.“Patients tend to withdraw, and families sometimes don’t understand why,” Dr Syed said.Where awareness remains limited, this can lead to stigma, misunderstanding, and delayed care. At the same time, it can add to the emotional and physical toll on families taking on the role of caregivers, managing medications, daily routines, and emotional needs.Everyday challengesParkinson’s affects even the simplest daily activities. Tasks like getting up from a chair, turning while walking, going to the washroom, or swallowing food can become difficult.“One misconception is that patients should try to move faster. This can actually increase the risk of falls,” Dr Syed cautioned.He emphasised the need to adapt the environment, from using assistive devices to modifying diets. Soft or semi-solid foods can help those with swallowing difficulties, while fibre-rich diets can ease constipation, a common issue.Physiotherapy and rehabilitation, he added, are essential in maintaining mobility and independence.The “million-dollar question”: Can Parkinson’s disease be cured?Dr Syed addressed one of the most frequently asked concerns, which he referred to as the “million-dollar question” asked by patients and families about whether Parkinson’s disease has a permanent cure. He explained that it is a progressive, degenerative disorder that worsens over time and currently has no definitive cure, though treatment can help manage symptoms and improve quality of life.“The million-dollar question being asked is, Doc, can I have a permanent cure? We all know Parkinson’s disease is a progressive disorder, a degenerative disorder, and as years go by, patients tend to deteriorate. There are staging processes of Parkinson’s being done. But the million-dollar question is: can I have a permanent cure? Unfortunately, at this point in time, there is no specific cure for Parkinson’s disease.”While there is currently no cure, a combination of medications, physical therapy, lifestyle adjustments, and, in some cases, surgical treatments can help manage symptoms and improve quality of life.Why this conversation matters nowOn World Parkinson’s Day, the focus is not just on the disease itself, but on awareness, early detection, and support systems.According to a study titled Neuropalliative Care for Parkinson’s Disease in India, the prevalence of Parkinson’s disease (PD) in India accounts for roughly 10% of the global burden, making it a significant public health concern.Experts at the 6th International Annual Symposium-2026 in Kerala said that India is expected to witness a surge in Parkinson’s cases in the coming years, which may pose a growing burden on families and caregivers. Yet awareness of early symptoms and non-motor signs remains low.The need is not only for better treatment, but for earlier recognition, reduced stigma, and stronger support networks, so that patients are not left navigating the condition in silence.Looking aheadWhile there is no cure yet, ongoing research offers cautious optimism. New drug delivery systems and emerging therapies, including stem cell research particularly induced pluripotent stem cells and human pluripotent stem cells, are being explored.For now, doctors emphasise a holistic approach, combining medication, mental health support, physiotherapy, and family involvement.“Parkinson’s is not just about tremors or movement. It affects the entire life of the patient and the family,” Dr Syed said.Parkinson’s disease is increasingly being recognised as a condition that begins long before visible symptoms such as tremors appear. Evidence suggests that more than half of dopamine-producing neurons in the brain may already be lost by the time a clinical diagnosis is made, underlining how silently the disease progresses in its early stages.This makes early recognition of non-motor symptoms such as sleep disturbances, loss of smell, mood changes, and constipation especially important. Greater awareness among families and caregivers can help ensure earlier medical attention, timely diagnosis, and better symptom management.At the same time, experts emphasise that medical care alone is not enough. Social acceptance and understanding play a critical role, as patients often face isolation due to slowed speech, reduced facial expression, and movement difficulties that are frequently misunderstood. Reducing stigma can go a long way in improving mental well-being and quality of life.About the AuthorOshin BhatiaOshin Bhatia is a budding journalist driven by an insatiable curiosity and hunger for knowledge. She loves diving deep into complex issues and expressing them through compelling narratives. Her interests span human-interest stories, the environment, and the intersections where people, places, and stories meet.Read MoreEnd of ArticleFollow Us On Social MediaVideosMirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North India123PhotostoriesDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit4 high-profile business family feuds that made headlines globally123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

Vamsikrishna09 mins mins

Meet Mr Bipin. He is nearing 62. These days, he pauses before signing his name, his hand trembling as he tries to steady the pen. What was once a simple task now takes great effort. His movements have slowed, his steps have become shorter, and at times he shuffles or loses balance without warning.Mr Bipin,…

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Ravindra Jadeja scripts history, becomes only second Indian to enter elite T20 club

Ravindra Jadeja scripts history, becomes only second Indian to enter elite T20 club

Vamsikrishna02 mins mins

Rajasthan Royals’ Ravindra Jadeja (AP Photo/Anupam Nath) Rajasthan Royals’ emphatic win in Guwahati was headlined by explosive batting, but it also quietly marked a significant personal milestone for Ravindra Jadeja. The all-rounder became only the second Indian after Hardik Pandya to complete the double of 4000 runs and 200 wickets in T20 cricket. The landmark…

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Vijay Varma recalls struggle after ‘Monsoon Shootout’; FTII graduate faced long idle period despite Cannes | Hindi Movie News

Vijay Varma recalls struggle after ‘Monsoon Shootout’; FTII graduate faced long idle period despite Cannes | Hindi Movie News

Vamsikrishna02 mins mins

Vijay Varma has earned acclaim for complex grey roles in projects like ‘Darlings’, ‘Dahaad’, and ‘IC 814: The Kandahar Hijack’. Varma has now opened up about the early struggles in his acting career. The versatile actor revealed how Bollywood typecast him in small supporting roles despite a prestigious Cannes premiere.In a recent interview, he spoke…

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Strong start to 2026: India Real Estate attracts .2 billion in private equity; what it means for buyers, investors

Strong start to 2026: India Real Estate attracts $1.2 billion in private equity; what it means for buyers, investors

Vamsikrishna04 mins mins

The Indian real estate market is witnessing a constant boom and flux. The market is witnessing the growth of several ew hot spots across the country. With the increased focus of the union government towards infrastructure growth in tier-2 and tier-3 cities, the market is likely to witness further development this year. Despite the fact…

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West Bengal CM Mamata Banerjee NEW DELHI: West Bengal chief minister and All India Trinamool Congress leader Mamata Banerjee on Saturday accused the Bharatiya Janata Party of attempting to get her candidature from the Bhabanipur assembly seat cancelled with the help of the Election Commission of India by filing “false cases”, alleging the move was thwarted by her party workers and the public. Addressing a poll rally in Keshiyari in Paschim Medinipur district, Mamata said, “The BJP, with the EC’s help, tried to invalidate my candidature from Bhabanipur by trying to file false cases against me, but we foiled their game plan.”She again accused the BJP of manipulating electoral rolls during the Special Intensive Revision (SIR) exercise. “Over 250 died due to SIR; out of 90 lakh deleted voters in Bengal, 60 lakh are Hindus, 30 lakh Muslims,” she said, news agency PTI reported.She alleged that the deletion of voter names was part of a broader strategy to influence poll outcomes. “They are deleting voters’ names. They are also planning to tinker with EVMs to turn the results in their favour,” Banerjee claimed.Raising concerns over identity and citizenship, she said, “Since we speak in Bengali, are we not Indians? Do we need to constantly prove citizenship?”The chief minister also criticised the BJP’s promise to implement a Uniform Civil Code (UCC) in the state if voted to power. She alleged that such a move would be “directed against backward communities” and aimed at curbing democratic rights.Mamata asserted that her party would resist any attempt to introduce the UCC in West Bengal and reiterated her political opposition to the BJP at both state and national levels.About the AuthorTOI News DeskThe TOI News Desk comprises a dedicated and tireless team of journalists who operate around the clock to deliver the most current and comprehensive news and updates to the readers of The Times of India worldwide. With an unwavering commitment to excellence in journalism, our team is at the forefront of gathering, verifying, and presenting breaking news, in-depth analysis, and insightful reports on a wide range of topics. The TOI News Desk is your trusted source for staying informed and connected to the ever-evolving global landscape, ensuring that our readers are equipped with the latest developments that matter most.”Read MoreEnd of ArticleFollow Us On Social MediaVideosMirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North India123PhotostoriesDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit4 high-profile business family feuds that made headlines globally123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

West Bengal CM Mamata Banerjee NEW DELHI: West Bengal chief minister and All India Trinamool Congress leader Mamata Banerjee on Saturday accused the Bharatiya Janata Party of attempting to get her candidature from the Bhabanipur assembly seat cancelled with the help of the Election Commission of India by filing “false cases”, alleging the move was thwarted by her party workers and the public. Addressing a poll rally in Keshiyari in Paschim Medinipur district, Mamata said, “The BJP, with the EC’s help, tried to invalidate my candidature from Bhabanipur by trying to file false cases against me, but we foiled their game plan.”She again accused the BJP of manipulating electoral rolls during the Special Intensive Revision (SIR) exercise. “Over 250 died due to SIR; out of 90 lakh deleted voters in Bengal, 60 lakh are Hindus, 30 lakh Muslims,” she said, news agency PTI reported.She alleged that the deletion of voter names was part of a broader strategy to influence poll outcomes. “They are deleting voters’ names. They are also planning to tinker with EVMs to turn the results in their favour,” Banerjee claimed.Raising concerns over identity and citizenship, she said, “Since we speak in Bengali, are we not Indians? Do we need to constantly prove citizenship?”The chief minister also criticised the BJP’s promise to implement a Uniform Civil Code (UCC) in the state if voted to power. She alleged that such a move would be “directed against backward communities” and aimed at curbing democratic rights.Mamata asserted that her party would resist any attempt to introduce the UCC in West Bengal and reiterated her political opposition to the BJP at both state and national levels.About the AuthorTOI News DeskThe TOI News Desk comprises a dedicated and tireless team of journalists who operate around the clock to deliver the most current and comprehensive news and updates to the readers of The Times of India worldwide. With an unwavering commitment to excellence in journalism, our team is at the forefront of gathering, verifying, and presenting breaking news, in-depth analysis, and insightful reports on a wide range of topics. The TOI News Desk is your trusted source for staying informed and connected to the ever-evolving global landscape, ensuring that our readers are equipped with the latest developments that matter most.”Read MoreEnd of ArticleFollow Us On Social MediaVideosMirzapur Horror Caught on CCTV: Attackers Panic After Killing Advocate As Bike Stalls While EscapingWatch PM Modi, Rahul Gandhi Engage In Candid Talk At Event To Pay Tribute To Jyotiba PhuleFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North India123PhotostoriesDivyanka Tripathi to Smriti Irani: TV queens who made us love sarees all over againTemples in India with incredible backstories that will leave you amazed24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit4 high-profile business family feuds that made headlines globally123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

Vamsikrishna02 mins mins

West Bengal CM Mamata Banerjee NEW DELHI: West Bengal chief minister and All India Trinamool Congress leader Mamata Banerjee on Saturday accused the Bharatiya Janata Party of attempting to get her candidature from the Bhabanipur assembly seat cancelled with the help of the Election Commission of India by filing “false cases”, alleging the move was…

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Apr 11, 2026, 13:26 IST

Apr 11, 2026, 13:26 IST

Vamsikrishna02 mins mins

India’s Ayush Shetty produced a remarkable performance to book his place in the final of the Badminton Asia Championships on Saturday, overcoming top seed and defending champion Kunlavut Vitidsarn in a gripping three-game contest. The victory ensures Ayush will return with at least a silver medal. Ranked world No. 25, Ayush relied on a combination…

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‘Open and welcoming to global capital’: Sebi chair Tuhin Kanta hails India’s finance landscape

‘Open and welcoming to global capital’: Sebi chair Tuhin Kanta hails India’s finance landscape

Vamsikrishna02 mins mins

Securities and Exchange Board of India (Sebi) chairman Tuhin Kanta Pandey hailed India’s financial landscape and assured global investors that the country continues to be an open and attractive destination. In a bid to draw in global capital from across the globe, he further pitched India’s strong macroeconomic fundamentals, rapidly expanding investor base, and a…

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Ranveer Singh hails Smriti Chauhan with heartfelt note after ‘Dhurandhar’ collaboration: ‘purest soul’

Ranveer Singh hails Smriti Chauhan with heartfelt note after ‘Dhurandhar’ collaboration: ‘purest soul’

Vamsikrishna02 mins mins

In a heartfelt social media tribute, actor Ranveer Singh celebrated costume designer Smriti Chauhan, describing her as a ‘purest soul’ and ‘mighty spirit’ following their remarkable collaboration on the film ‘Dhurandhar’. He expressed his deep gratitude for her vibrant energy, acknowledging her masterful creation of 250 unique looks for his character, Hamza. Ranveer Singh shared…

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