Japan sits on four tectonic plates and is hit by around 1,500 earthquakes every year, yet its cities rarely collapse. Here’s the incredible reason why

Japan sits on four tectonic plates and is hit by around 1,500 earthquakes every year, yet its cities rarely collapse. Here’s the incredible reason why

Japan experiences around 1,500 earthquakes that are strong enough to be felt every year, a staggering figure that would seem disastrous for most countries. Yet, despite sitting at one of the most seismically active places on Earth, Japan’s cities rarely witness widespread building collapses after major earthquakes. The contrast became even more striking after recent…

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Representative image NEW DELHI: A commonly used spinal anaesthesia drug has come under scrutiny after the Indian Society of Anaesthesiologists (ISA) advised doctors across the country to immediately stop using Themis-manufactured bupivacaine following reports of serious adverse events.In an urgent advisory issued on Monday, the ISA asked anaesthesiologists nationwide not to use bupivacaine manufactured by Themis for spinal anaesthesia or any other purpose until further notice, saying the precautionary measure had been taken in the interest of patient safety while investigations are underway.Bupivacaine is among the most commonly used local anaesthetics for spinal and epidural anaesthesia during surgeries. The ISA said the advisory followed reports of serious adverse events linked to the Themis-manufactured drug, but did not disclose the number or nature of the events. Investigations are continuing.Hospitals have also been advised to identify and segregate existing stocks of the drug, withdraw them from clinical use and switch to alternative approved brands for spinal anaesthesia procedures.A separate caution notice issued by the ISA’s Hyderabad Metro City Branch directed consultants, resident doctors, anaesthesia technicians and operation theatre personnel to immediately suspend the use of Themis Bupivacaine for spinal anaesthesia. It said no ampoules of the product should be used for neuraxial administration until an official clearance is issued, and any inadvertent use must be reported immediately to the head of the department.”This is a precautionary advisory issued in the interest of patient safety. Reports of serious adverse events have been received from multiple hospitals, and until the investigation is completed, we have advised doctors to stop using the product,” said Dr Sherry Mathews, president of the Hyderabad Metro City Branch of the Indian Society of Anaesthesiologists.Get the latest India news and live updates. Download the TOI App.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideosWhy Nayara Reduced Fuel Prices But PSU Oil Companies Didn’t?Dhaka Threatens Action Against Media Airing Sheikh Hasina’s Statements After Return ClaimSpecialised ‘Baaz Battalions’ to Strengthen Border Monitoring, ISR and Battlefield Awareness’Break Silos, Self-Reliance’: PM Modi Holds High-Level Meet With Union SecretariesMumbai Horror: School Bus Crushed By Falling Tree In Mumbai; One Child Dead, Five Injured’Kashmir Is Not Part Of Pakistan’: PoJK Protesters Warn IslamabadAfter Converting To Islam For Love, UP’s Ayush Malik Returns To Hinduism | Watch’This Is Bigger Than Dharmendra Pradhan’: Students Demand Reforms Not ‘Political Damage Control’Another Blow To Uddhav Thackeray: Prominent Mumbai Leader Sachin Ahir Switches Sides | WatchRs 65 Lakh House, SUV, Farmhouse: Ram Temple Donation Theft Accused’s Assets Under Scanner123PhotostoriesHighest-protein Indian dals ranked from best to leastWhat would you do? My colleague constantly asks about my personal life; 5 women share how they reactedFrom Naomi Osaka to Maria Sharapova: Five times Tennis stars paid homage to pop culture with their on-court fits7 countries where children walk to school alone and why parents trust themJuly gardening guide: 7 flowers, fruits, and vegetables to plant in the UKThis Amritsari-style Eggless Potato Mayonnaise by Chef Vikas Khanna is a treat for vegetariansWhy some people leave your texts unread for hours? Psychology says it may not be about ‘rejection’ after allFrom 124-Year-Old Plum Cakes to Legendary Biscuits: 5 of India’s oldest bakeries every food lover needs to try60-second money lesson: What your UPI history reveals about your spending habits9 actors who learned real skills for roles: Cillian Murphy, Kate Winslet, Jenna Ortega and more123Hot PicksLPG gas priceCBSE best marks ruleCBSE Class 12 supplementary exam 202Ram Temple donation theftMumbai RainsNew visa ruleZohran MamdaniNayara petrol priceAP EAPCET Result 2026Top TrendingNayara energy petrol priceLPG priceSonam RaghuvanshiFIFA World Cup 2026Monaco BlastBengaluru TechieAnukalp MishraSergei IvanovMK StalinJosh Hokit

Representative image NEW DELHI: A commonly used spinal anaesthesia drug has come under scrutiny after the Indian Society of Anaesthesiologists (ISA) advised doctors across the country to immediately stop using Themis-manufactured bupivacaine following reports of serious adverse events.In an urgent advisory issued on Monday, the ISA asked anaesthesiologists nationwide not to use bupivacaine manufactured by Themis for spinal anaesthesia or any other purpose until further notice, saying the precautionary measure had been taken in the interest of patient safety while investigations are underway.Bupivacaine is among the most commonly used local anaesthetics for spinal and epidural anaesthesia during surgeries. The ISA said the advisory followed reports of serious adverse events linked to the Themis-manufactured drug, but did not disclose the number or nature of the events. Investigations are continuing.Hospitals have also been advised to identify and segregate existing stocks of the drug, withdraw them from clinical use and switch to alternative approved brands for spinal anaesthesia procedures.A separate caution notice issued by the ISA’s Hyderabad Metro City Branch directed consultants, resident doctors, anaesthesia technicians and operation theatre personnel to immediately suspend the use of Themis Bupivacaine for spinal anaesthesia. It said no ampoules of the product should be used for neuraxial administration until an official clearance is issued, and any inadvertent use must be reported immediately to the head of the department.”This is a precautionary advisory issued in the interest of patient safety. Reports of serious adverse events have been received from multiple hospitals, and until the investigation is completed, we have advised doctors to stop using the product,” said Dr Sherry Mathews, president of the Hyderabad Metro City Branch of the Indian Society of Anaesthesiologists.Get the latest India news and live updates. Download the TOI App.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideosWhy Nayara Reduced Fuel Prices But PSU Oil Companies Didn’t?Dhaka Threatens Action Against Media Airing Sheikh Hasina’s Statements After Return ClaimSpecialised ‘Baaz Battalions’ to Strengthen Border Monitoring, ISR and Battlefield Awareness’Break Silos, Self-Reliance’: PM Modi Holds High-Level Meet With Union SecretariesMumbai Horror: School Bus Crushed By Falling Tree In Mumbai; One Child Dead, Five Injured’Kashmir Is Not Part Of Pakistan’: PoJK Protesters Warn IslamabadAfter Converting To Islam For Love, UP’s Ayush Malik Returns To Hinduism | Watch’This Is Bigger Than Dharmendra Pradhan’: Students Demand Reforms Not ‘Political Damage Control’Another Blow To Uddhav Thackeray: Prominent Mumbai Leader Sachin Ahir Switches Sides | WatchRs 65 Lakh House, SUV, Farmhouse: Ram Temple Donation Theft Accused’s Assets Under Scanner123PhotostoriesHighest-protein Indian dals ranked from best to leastWhat would you do? My colleague constantly asks about my personal life; 5 women share how they reactedFrom Naomi Osaka to Maria Sharapova: Five times Tennis stars paid homage to pop culture with their on-court fits7 countries where children walk to school alone and why parents trust themJuly gardening guide: 7 flowers, fruits, and vegetables to plant in the UKThis Amritsari-style Eggless Potato Mayonnaise by Chef Vikas Khanna is a treat for vegetariansWhy some people leave your texts unread for hours? Psychology says it may not be about ‘rejection’ after allFrom 124-Year-Old Plum Cakes to Legendary Biscuits: 5 of India’s oldest bakeries every food lover needs to try60-second money lesson: What your UPI history reveals about your spending habits9 actors who learned real skills for roles: Cillian Murphy, Kate Winslet, Jenna Ortega and more123Hot PicksLPG gas priceCBSE best marks ruleCBSE Class 12 supplementary exam 202Ram Temple donation theftMumbai RainsNew visa ruleZohran MamdaniNayara petrol priceAP EAPCET Result 2026Top TrendingNayara energy petrol priceLPG priceSonam RaghuvanshiFIFA World Cup 2026Monaco BlastBengaluru TechieAnukalp MishraSergei IvanovMK StalinJosh Hokit

NEW DELHI: A commonly used spinal anaesthesia drug has come under scrutiny after the Indian Society of Anaesthesiologists (ISA) advised doctors across the country to immediately stop using Themis-manufactured bupivacaine following reports of serious adverse events.In an urgent advisory issued on Monday, the ISA asked anaesthesiologists nationwide not to use bupivacaine manufactured by Themis for…

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Nayara Energy cuts petrol price by Rs 5 per litre, diesel rates slashed by Rs 3; first fuel price reduction in over 2 years

Nayara Energy cuts petrol price by Rs 5 per litre, diesel rates slashed by Rs 3; first fuel price reduction in over 2 years

Nayara Energy cuts fuel and diesel prices NEW DELHI: Nayara Energy, India’s largest private fuel retailer, on Wednesday announced a reduction in petrol and diesel prices. Petrol prices have been cut by Rs 5 per litre and diesel by Rs 3 per litre across its nationwide retail network, becoming the first fuel retailer in more…

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Why is CA Day celebrated on July 1? History, significance, theme, date and key facts explained

Why is CA Day celebrated on July 1? History, significance, theme, date and key facts explained

Observed every year on July 1, CA Day commemorates the establishment of the Institute of Chartered Accountants of India (ICAI) under the Chartered Accountants Act, 1949. The occasion celebrates the contribution of Chartered Accountants to India’s financial system while exploring the profession’s origins, ICAI’s role, its guiding motto, and the significance of the annual observance….

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Kate Middleton faces ‘no end of anxiety’ as Meghan Markle’s return reportedly revives royal tensions

Kate Middleton faces ‘no end of anxiety’ as Meghan Markle’s return reportedly revives royal tensions

Reports of a possible family reunion have once again put the spotlight on the Princess of Wales and the Duchess of Sussex’s complicated history.Image credit (Instagram) Kate Middleton is struggling to move past years of friction with Meghan Markle as Prince Harry plans a family return to the United Kingdom. The Princess of Wales is…

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Trump announces first-ever two-day Republican midterm convention in Dallas

Trump announces first-ever two-day Republican midterm convention in Dallas

Trump’s announcement breaks the tradition of the Republican Party holding national conventions only during presidential election years to formally nominate its White House candidate Republicans will hold their first-ever midterm convention in Dallas, Texas, on September 9 and 10, US President Donald Trump announced on Tuesday, saying the unprecedented gathering would celebrate his administration’s achievements…

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Faissal Khan apologises to Aamir Khan and family ahead of actor’s wedding: ‘In anger and pain, I said many things’

Faissal Khan apologises to Aamir Khan and family ahead of actor’s wedding: ‘In anger and pain, I said many things’

Faissal Khan apologises to Aamir Khan and family ahead of actor’s wedding: ‘In anger and pain, I said many things’ Ahead of Aamir Khan’s reported wedding, his brother Faissal Khan has issued a public apology to the actor and their family, months after making serious allegations against them. Faissal admitted that speaking against his loved…

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Scientists may have finally solved the mystery behind Yellowstone’s 640,000-year-old mega eruption, revealing what really fueled it

Scientists may have finally solved the mystery behind Yellowstone’s 640,000-year-old mega eruption, revealing what really fueled it

For decades, Yellowstone has been held up as one of the clearest examples of a volcanic system fed by an immense column of hot rock rising from deep within the Earth. That picture has shaped scientific thinking about why the region remains volcanically active and how its future might unfold. A newly published study, however,…

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Akshay Kumar on ‘Welcome to the Jungle’ box office success: ‘Every Friday still feels like an exam result’

Akshay Kumar on ‘Welcome to the Jungle’ box office success: ‘Every Friday still feels like an exam result’

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What is donghua? A beginner’s guide to Chinese animation and must-watch series

What is donghua? A beginner’s guide to Chinese animation and must-watch series

Japanese anime has dominated the global animation scene for decades, but in recent years, donghua has emerged as a worthy contender. With breathtaking visuals, unique storytelling, and a growing international fanbase, Chinese animation is producing some of the most exciting fantasy, action, and mystery series available today. If you’ve ever wondered what donghua is or…

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US is already deploying weapons in western Pacific to defend Taiwan from China

US is already deploying weapons in western Pacific to defend Taiwan from China

A Navy-Marine Expeditionary Ship Interdiction System forward deployed in the Pacific. (Imafe credit: US DoW) The US is already deploying weapons in the western Pacific to defend Taiwan from ChinaAs tensions due to China’s aspirations rise in the Indo-Pacific region, especially around Taiwan, the US Marine Corps has deployed new weapon systems in the Pacific….

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