File photo NEW DELHI: The new generation of weight-loss injections — already popular globally — is now showing strong results in Indian patients too. A fresh study from a Delhi hospital finds that more than 4 in 10 people lost at least 10% of their body weight, a level doctors say can significantly improve overall health.The research, conducted by doctors at Max Super Speciality Hospital, Saket, led by endocrinologist Dr Ambrish Mithal and published in the Indian Journal of Endocrinology and Metabolism, tracked 150 overweight and obese adults on these therapies in routine clinical practice.On average, patients lost about 8% of their body weight in six months — roughly 6 to 10 kilos for many. Nearly three-fourths lost at least 5%, considered the minimum for health benefits such as better sugar control and reduced heart risk. Experts said the findings are based on short-term follow-up of about six months. “This is not the final weight loss. With longer follow-up, especially at one year, the reduction is likely to be significantly greater,” said Dr Ambrish Mithal.But the results were not the same for everyone.People without diabetes responded far better, losing almost double the weight compared to those with diabetes. The study suggests this could be because of deeper metabolic changes and insulin resistance in diabetic patients.The type of drug also mattered. Patients on tirzepatide — a newer dual-action injection — saw greater and faster weight loss than those on semaglutide. Many reached the 10% mark within 9 to 10 months, though doctors caution that the process is gradual, not instant.The study also offers a reality check. Younger patients and those trying these drugs for the first time saw quicker results, while those who had used similar medications earlier lost weight more slowly.Side effects like nausea, bloating and constipation were common, especially in the early phase, but were manageable and did not force patients to stop treatment.Unlike clinical trials, which are tightly controlled, this study reflects what happens in everyday life — where people may miss doses, vary their diet or have other health conditions. Even then, the results held up, giving doctors confidence that these drugs work beyond ideal settings.With obesity and diabetes rising sharply in India, the findings mark a shift in how weight loss is being approached — from diet and exercise alone to medical support that can make a measurable difference.Experts said that the message is simple: these injections are not magic fixes, but when used consistently and alongside lifestyle changes, they can lead to steady, meaningful weight loss over time.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideosFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North IndiaCentre Notifies CAPF General Administration Act 2026; Families, Retired Officers Protest in DelhiJustice Yashwant Varma Resigns Amid Cash Row — Why He Stepped Down On Day Of Impeachment Defence123Photostories24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit5 things that make Bandhavgarh National Park irresistible to nature loversGold or platinum with diamonds: Which one actually makes you look richer?Chef Sanjeev Kapoor shares secrets on how to use moong (whole, split with skin, and split skinless) for maximum benefits123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case

File photo NEW DELHI: The new generation of weight-loss injections — already popular globally — is now showing strong results in Indian patients too. A fresh study from a Delhi hospital finds that more than 4 in 10 people lost at least 10% of their body weight, a level doctors say can significantly improve overall health.The research, conducted by doctors at Max Super Speciality Hospital, Saket, led by endocrinologist Dr Ambrish Mithal and published in the Indian Journal of Endocrinology and Metabolism, tracked 150 overweight and obese adults on these therapies in routine clinical practice.On average, patients lost about 8% of their body weight in six months — roughly 6 to 10 kilos for many. Nearly three-fourths lost at least 5%, considered the minimum for health benefits such as better sugar control and reduced heart risk. Experts said the findings are based on short-term follow-up of about six months. “This is not the final weight loss. With longer follow-up, especially at one year, the reduction is likely to be significantly greater,” said Dr Ambrish Mithal.But the results were not the same for everyone.People without diabetes responded far better, losing almost double the weight compared to those with diabetes. The study suggests this could be because of deeper metabolic changes and insulin resistance in diabetic patients.The type of drug also mattered. Patients on tirzepatide — a newer dual-action injection — saw greater and faster weight loss than those on semaglutide. Many reached the 10% mark within 9 to 10 months, though doctors caution that the process is gradual, not instant.The study also offers a reality check. Younger patients and those trying these drugs for the first time saw quicker results, while those who had used similar medications earlier lost weight more slowly.Side effects like nausea, bloating and constipation were common, especially in the early phase, but were manageable and did not force patients to stop treatment.Unlike clinical trials, which are tightly controlled, this study reflects what happens in everyday life — where people may miss doses, vary their diet or have other health conditions. Even then, the results held up, giving doctors confidence that these drugs work beyond ideal settings.With obesity and diabetes rising sharply in India, the findings mark a shift in how weight loss is being approached — from diet and exercise alone to medical support that can make a measurable difference.Experts said that the message is simple: these injections are not magic fixes, but when used consistently and alongside lifestyle changes, they can lead to steady, meaningful weight loss over time.About the AuthorAnuja JaiswalAnuja Jaiswal is a Senior Assistant Editor at The Times of India, with an impressive 18-year career in narrative journalism. She specializes in health and heritage reporting, expertly simplifying complex health information to make it engaging and understandable for readers. Her deep dives into heritage topics are well-researched, resulting in captivating narratives that resonate with her audience. Over the years, she has worked in Chandigarh, Chhattisgarh and West UP, gaining diverse on-ground experience that shapes her storytelling.Read MoreEnd of ArticleFollow Us On Social MediaVideosFrom Prayer To Panic: Final Moments Before Mathura Boat Tragedy Emerges, Rescue Operations ContinueIndia-US Ties Get Real Boost As Vikram Misri Wraps Up Key Visit After Talks On LPG, Nuclear PowerIndia Walks Diplomatic Tightrope, Condemns Bloodshed In Lebanon, But Does Not Name IsraelDelhi Police Crack Down on ISI-Linked Spy Module, 10 Arrested; Second Network Busted After Pan-India Surveillance Plot’Chokepoints Now A Global Anxiety’: Jaishankar Invokes West Asia Crisis At Indian Ocean ConferenceMathura: Boat Carrying Devotees Capsizes In Yamuna; 10 Bodies Recovered, Rescue Ops OnQatar Assures Reliable Energy Supply To India Amid West Asia Crisis After Hardeep Puri’s Doha VisitPakistan-ISI Spy Network Busted: 11 Arrested For Recce Of Military Sites Across North IndiaCentre Notifies CAPF General Administration Act 2026; Families, Retired Officers Protest in DelhiJustice Yashwant Varma Resigns Amid Cash Row — Why He Stepped Down On Day Of Impeachment Defence123Photostories24 hours in Delhi: 10 summer-friendly street foods to enjoy in the national capitalCute first and middle names for kids born on SaturdayHow to make Kathal ke Kebab for weekend lunch6 smart small balcony layouts that maximise space effortlessly8 modern and not-so-common baby names for kids born on a FridayFrom Vivek Dahiya getting emotional during Divyanka Tripathi’s pregnancy scan to pampering her midnight cravings, the couple share their journeyHow to differentiate between naturally and chemically ripened banana: FSSAI’s rulebook on ripening temperature for the fruit5 things that make Bandhavgarh National Park irresistible to nature loversGold or platinum with diamonds: Which one actually makes you look richer?Chef Sanjeev Kapoor shares secrets on how to use moong (whole, split with skin, and split skinless) for maximum benefits123Hot PicksIran war ceasefirePAN Card application 2026Purple cap winnerOrange cap winnerIPL Points TablePublic holidays April 2026Bank Holidays AprilTop TrendingStephen Curry charityLaura Loomer reactionIndia Lebanon civilianRajouri grenade recoveryUS stock marketPAN Card application 2026Hinjewadi Metro lineUS inflationSchool Holidays in AprilLaken Snelling case


Weight-loss injections deliver in real life: 4 in 10 Indians shed 10% body weight

NEW DELHI: The new generation of weight-loss injections — already popular globally — is now showing strong results in Indian patients too. A fresh study from a Delhi hospital finds that more than 4 in 10 people lost at least 10% of their body weight, a level doctors say can significantly improve overall health.The research, conducted by doctors at Max Super Speciality Hospital, Saket, led by endocrinologist Dr Ambrish Mithal and published in the Indian Journal of Endocrinology and Metabolism, tracked 150 overweight and obese adults on these therapies in routine clinical practice.On average, patients lost about 8% of their body weight in six months — roughly 6 to 10 kilos for many. Nearly three-fourths lost at least 5%, considered the minimum for health benefits such as better sugar control and reduced heart risk. Experts said the findings are based on short-term follow-up of about six months. “This is not the final weight loss. With longer follow-up, especially at one year, the reduction is likely to be significantly greater,” said Dr Ambrish Mithal.But the results were not the same for everyone.People without diabetes responded far better, losing almost double the weight compared to those with diabetes. The study suggests this could be because of deeper metabolic changes and insulin resistance in diabetic patients.The type of drug also mattered. Patients on tirzepatide — a newer dual-action injection — saw greater and faster weight loss than those on semaglutide. Many reached the 10% mark within 9 to 10 months, though doctors caution that the process is gradual, not instant.The study also offers a reality check. Younger patients and those trying these drugs for the first time saw quicker results, while those who had used similar medications earlier lost weight more slowly.Side effects like nausea, bloating and constipation were common, especially in the early phase, but were manageable and did not force patients to stop treatment.Unlike clinical trials, which are tightly controlled, this study reflects what happens in everyday life — where people may miss doses, vary their diet or have other health conditions. Even then, the results held up, giving doctors confidence that these drugs work beyond ideal settings.With obesity and diabetes rising sharply in India, the findings mark a shift in how weight loss is being approached — from diet and exercise alone to medical support that can make a measurable difference.Experts said that the message is simple: these injections are not magic fixes, but when used consistently and alongside lifestyle changes, they can lead to steady, meaningful weight loss over time.



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